01 / RISK PREDICTION
Predicting HG before pregnancy
Developing preconception risk stratification using genetic information and clinical history.
Branham & Fejzo · ICHG 2026 presentation
Related readingCurrent directions
The next questions.
Building on genetic discoveries to advance prediction, prevention, and care for adverse pregnancy conditions.
02 / PREVENTION
Exploring prevention with metformin
Investigating pre-pregnancy metformin and severe nausea and vomiting of pregnancy.
Rosa et al. · PPHS Research Symposium 2026
Related reading03 / TRANSLATIONAL RESEARCH
GDF15 and treatment response
Examining glucocorticoid treatment, circulating GDF15 concentrations, and changes in HG symptoms.
Thompson et al. · AJOG 2026
Related reading04 / GENETIC EPIDEMIOLOGY
Genetic variation across ancestries
Understanding risk pathways through multi-ancestry genome-wide association studies of severe pregnancy nausea and vomiting.
Fejzo et al. · Nature Genetics 2026
Related reading05 / MATERNAL HEALTH
Pregnancy proteins and preeclampsia
Studying how circulating HG and preeclampsia risk proteins change during pregnancy.
Mescioglu et al. · PPHS Research Symposium 2026
06 / CHILD OUTCOMES
Genetics and infant birthweight
Examining progesterone receptor gene risk variants and birthweight in pregnancies affected by HG.
Mescioglu, Branham & Fejzo · ICHG 2026
Research directions drawn from the supplied CV. Investigational approaches are not treatment recommendations.